All AbMole products are for research use only, cannot be used for human consumption.
Carmofur is a pyrimidine analog that is a prodrug of 5-fluorouracil (5-FU), which inhibits DNA Synthesis and has better antiproliferative activity than 5-FU. Carmofur is an inhibitor of Acidic Ceramidase (ASAH1) and a potential lead compound for non-cancer diseases such as Krabbe disease, acute lung injury (ALI), Parkinson's disease (PD), dementia, etc. Carmofur also has antifungal and antimicrobial properties.
J Integr Plant Biol. 2024 Jan.
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Carmofur purchased from AbMole
| Molecular Weight | 257.26 |
| Formula | C11H16FN3O3 |
| CAS Number | 61422-45-5 |
| Solubility (25°C) | DMSO 40 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[3] Alexey Dementiev, et al. Molecular Mechanism of Inhibition of Acid Ceramidase by Carmofur
[4] S Matsumoto, et al. Carmofur-induced leukoencephalopathy: MRI
[5] S Kuzuhara, et al. Subacute leucoencephalopathy induced by carmofur, a 5-fluorouracil derivative
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Products are for research use only. Not for human use. We do not sell to patients.
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