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UAMC-3203 is an improved ferroptosis inhibitor, with an IC50 value of 10 nM in IMR-32 neuroblastoma cells. In vivo, UAMC-3203 significantly lowers the plasma levels of lactate dehydrogenase (LDH) in mice. It is rapidly removed from the bloodstream and redistributed into various tissues, as can be expected for lipophilic basic compounds.
| Molecular Weight | 471.66 |
| Formula | C25H37N5O2S |
| CAS Number | 2271358-64-4 |
| Solubility (25°C) | DMSO ≥ 60 mg/mL |
| Storage | 2-8°C, protect from light, sealed |
| Related Ferroptosis Products |
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| HBED
HBED is a potent iron chelator. |
| viFSP1
viFSP1 is a species-independent inhibitor of FSP1 that induces ferroptosis in FSP1-dependent cells. |
| icFSP1
icFSP1 is a potent ferroptosis suppressor protein-1 (FSP1) inhibitor. |
| (R)-HTS-3
(R)-HTS-3 is an lysophosphatidylcholine acyltransferase 3 (LPCAT3) inhibitor, with an IC50 of 0.09 μM. |
| CuATSP
CuATSP is a potent inhibitor of ferroptosis. |
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