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Tutuilamide A 

Cat. No. M29801

All AbMole products are for research use only, cannot be used for human consumption.

Tutuilamide A  Structure

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Quality Control & Documentation
Biological Activity

Tutuilamide A is a potent porcine pancreatic elastase (PPE) inhibitor, with an IC50 of 1.2 nM. Tutuilamide A also inhibits human neutrophil elastase (HNE; IC50=0.73 nM) and kallikrein 7 (KLK7; IC50=5.0 nM).

Chemical Information
Molecular Weight 1021.59
Formula C51H69ClN8O12
CAS Number 2756129-42-5
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Qi-Yin Chen, et al. Bioorg Med Chem. Ahp-Cyclodepsipeptides as tunable inhibitors of human neutrophil elastase and kallikrein 7: Total synthesis of tutuilamide A, serine protease selectivity profile and comparison with lyngbyastatin 7

[2] Lena Keller, et al. ACS Chem Biol. Tutuilamides A-C: Vinyl-Chloride-Containing Cyclodepsipeptides from Marine Cyanobacteria with Potent Elastase Inhibitory Properties

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Abmole Inhibitor Catalog




Keywords: Tutuilamide A  supplier, Elastase, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.


 
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