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Cat. No. M4326
Chrysophanol-8-O-β-D-glucopyranoside Structure
Size Price Availability Quantity
5mg USD 280  USD280 In stock
10mg USD 440  USD440 In stock
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Quality Control & Documentation
Biological Activity

Chrysophanol 8-O-glucoside is derived from the root of Rumex acetosa and has moderate elastase inhibitory activity.

Chemical Information
Molecular Weight 416.39
Formula C21H20O9
CAS Number 13241-28-6
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.


[1] Meichen Liu, et al. A Cell-Based Metabonomics Approach to Investigate the Varied Influences of Chrysophanol-8-O-β-D-Glucoside With Different Concentrations on L-02 Cells

[2] Cun Zhang, et al. Two new anthraquinone glycosides from the roots of Rheum palmatum

[3] Myung Sun Lee, et al. Anti-diabetic properties of chrysophanol and its glucoside from rhubarb rhizome

[4] Tran Minh Ngoc, et al. Lipoxygenase inhibitory constituents from rhubarb

[5] D H Kim, et al. Metabolism of rhaponticin and chrysophanol 8-o-beta-D-glucopyranoside from the rhizome of rheum undulatum by human intestinal bacteria and their anti-allergic actions

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Abmole Inhibitor Catalog

Keywords: Chrysophanol-8-O-β-D-glucopyranoside supplier, Elastase, inhibitors, activators

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