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Elastase Elastase

Inhibitors

Cat.No.  Name Information
M5402 Alvelestat (AZD9668) Alvelestat (AZD9668) is an oral, highly selective inhibitor of neutrophil elastase (NE) with IC50 and Ki of 12 nM and 9.4 nM, at least 600-fold more selective over other serine proteases.
M14333 DMP 777 DMP 777 is a potent, selective, and orally active human leukocyte elastase (HLE) inhibitor.
M14332 BAY-85-8501 BAY-85-8501 is a selective, reversible and potent inhibitor of Human Neutrophil Elastase (HNE), with an IC50 of 65 pM.
M9550 Sivelestat Sivelestat (ONO5046; LY544349; EI546) is a potent and selective inhibitor of neutrophil elastase with IC50 of 44nM.
M5402 Alvelestat (AZD9668) Alvelestat (AZD9668) is an oral, highly selective inhibitor of neutrophil elastase (NE) with IC50 and Ki of 12 nM and 9.4 nM, at least 600-fold more selective over other serine proteases.
M5148 GW311616 hydrochloride GW311616 HCl (GW311616A) is a potent, intracellular, orally bioavailable, long duration inhibitor of human neutrophil elastase(HNE) with IC50 of 22 nM.
M5147 GW311616 GW311616 is a potent, intracellular, orally bioavailable, long duration inhibitor of human neutrophil elastase(HNE) with IC50 of 22 nM.
M4326 Chrysophanol-8-O-β-D-glucopyranoside Chrysophanol 8-O-glucoside is derived from the root of Rumex acetosa and has moderate elastase inhibitory activity.



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