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Elastase Elastase

Cat.No.  Name Information
M9550 Sivelestat Sivelestat (ONO5046; LY544349; EI546) is a potent and selective inhibitor of neutrophil elastase with IC50 of 44nM.
M5966 Sivelestat sodium tetrahydrate Sivelestat sodium tetrahydrate is a competitive inhibitor of human neutrophil elastase, with an IC50 of 44 nM and a Ki of 200 nM. Sivelestat (EI546) sodium tetrahydrate also inhibits leukocyte elastase obtained from rabbit, rat, hamster and mouse.
M5402 Alvelestat (AZD9668) Alvelestat (AZD9668) is an oral, highly selective inhibitor of neutrophil elastase (NE) with IC50 and Ki of 12 nM and 9.4 nM, at least 600-fold more selective over other serine proteases.
M7297 Sivelestat sodium salt Sivelestat sodium salt is a selective leukocyte elastase inhibitor.
M5148 GW311616 hydrochloride GW311616 HCl (GW311616A) is a potent, intracellular, orally bioavailable, long duration inhibitor of human neutrophil elastase(HNE) with IC50 of 22 nM.
M5147 GW311616 GW311616 is a potent, intracellular, orally bioavailable, long duration inhibitor of human neutrophil elastase(HNE) with IC50 of 22 nM.
M4326 Chrysophanol-8-O-β-D-glucopyranoside Chrysophanol 8-O-glucoside is derived from the root of Rumex acetosa and has moderate elastase inhibitory activity.
M52640 Ala-Ala-Pro-Val-chloromethylketone Ala-Ala-Pro-Val-chloromethylketone is an irreversible human neutrophil elastase (NE) inhibitor for use in the study of chronic inflammatory airway diseases.
M52639 MeOSuc-Ala-Ala-Pro-Met-AMC MeOSuc-Ala-Ala-Pro-Met-AMC is a peptide substrate of elastases and chymotrypsin-like serine peptidases.
M52638 Suc-Ala-Ala-Pro-Val-AMC Suc-Ala-Ala-Pro-Val-AMC, a tetrapeptide, is an elastasesubstrate.
M52637 Suc-Ala-Ala-Ala-AMC Suc-Ala-Ala-Ala-AMC is a peptide substrate of elastase or elastase-like.
M52636 Suc-Ala-Pro-Ala-AMC Suc-Ala-Pro-Ala-AMC is a tripeptide substrate of elastase.
M52635 MeOSuc-AAPV-CMK MeOSuc-AAPV-CMK (Elastase Inhibitor III) is an elastase inhibitor.
M52634 Suc-AAP-Abu-pNA Suc-AAP-Abu-pNA (Colorimetric Elastase Substrate) is a specific substrate for pancreatic elastase.
M52633 Lonodelestat Lonodelestat (POL6014) is a potent, orally active and selective peptide inhibitor of human neutrophil elastase (hNE).
M52632 Tiprelestat Tiprelestat is a potent human neutrophil elastase inhibitor.
M42348 Neutrophil elastase inhibitor 4 Neutrophil elastase inhibitor 4 is a competitive human neutrophil elastase (HNE) inhibitor (IC50: 42.30 nM, Ki: 8.04 nM).
M42347 Aristololactam IIIa Aristololactam IIIa exhibits significant inhibitory effects on superoxide anion generation and elastase release with IC50 values of 0.12 and 0.20 μg/mL, respectively.
M42346 KLK7/ELA2-IN-1 KLK7/ELA2-IN-1 is a potent kallikrein-related peptidase 7 (KLK7) and epidermal elastase 2 (ELA2) inhibitor with IC50s of 6 nM and 55 nM, respectively.
M39077 Skullcapflavone I Skullcapflavone I can be isolated from A. nallamalayana. Skullcapflavone I inhibits collagenase and elastase enzyme with IC50s of 106.74 μM and 186.70 μM. Skullcapflavone I has anticancer activities by down-regulating miR-23a.




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