Inhibitors
Cat.No. | Name | Information |
---|---|---|
M5402 | Alvelestat (AZD9668) | Alvelestat (AZD9668) is an oral, highly selective inhibitor of neutrophil elastase (NE) with IC50 and Ki of 12 nM and 9.4 nM, at least 600-fold more selective over other serine proteases. |
M14333 | DMP 777 | DMP 777 is a potent, selective, and orally active human leukocyte elastase (HLE) inhibitor. |
M14332 | BAY-85-8501 | BAY-85-8501 is a selective, reversible and potent inhibitor of Human Neutrophil Elastase (HNE), with an IC50 of 65 pM. |
M9550 | Sivelestat | Sivelestat (ONO5046; LY544349; EI546) is a potent and selective inhibitor of neutrophil elastase with IC50 of 44nM. |
M5402 | Alvelestat (AZD9668) | Alvelestat (AZD9668) is an oral, highly selective inhibitor of neutrophil elastase (NE) with IC50 and Ki of 12 nM and 9.4 nM, at least 600-fold more selective over other serine proteases. |
M5148 | GW311616 hydrochloride | GW311616 HCl (GW311616A) is a potent, intracellular, orally bioavailable, long duration inhibitor of human neutrophil elastase(HNE) with IC50 of 22 nM. |
M5147 | GW311616 | GW311616 is a potent, intracellular, orally bioavailable, long duration inhibitor of human neutrophil elastase(HNE) with IC50 of 22 nM. |
M4326 | Chrysophanol-8-O-β-D-glucopyranoside | Chrysophanol 8-O-glucoside is derived from the root of Rumex acetosa and has moderate elastase inhibitory activity. |
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