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KLK7/ELA2-IN-1

Cat. No. M42346

All AbMole products are for research use only, cannot be used for human consumption.

KLK7/ELA2-IN-1 Structure

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Quality Control & Documentation
Biological Activity

KLK7/ELA2-IN-1 is a potent kallikrein-related peptidase 7 (KLK7) and epidermal elastase 2 (ELA2) inhibitor with IC50s of 6 nM and 55 nM, respectively.

Chemical Information
Molecular Weight 929.11
Formula C46H72N8O12
CAS Number 1122484-55-2
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Joseph Chavarria-Smith et al. Sci Transl Med. Dual antibody inhibition of KLK5 and KLK7 for Netherton syndrome and atopic dermatitis

[2] Erhua Chen et al. Open Med (Wars). Analysis of expression and prognosis of KLK7 in ovarian cancer

[3] Hyunjin Yeo et al. Biochem Biophys Res Commun. EGR-1 acts as a transcriptional activator of KLK7 under IL-13 stimulation

[4] Ilangovan Raju et al. Biol Chem. Epigenetic regulation of KLK7 gene expression in pancreatic and cervical cancer cells

[5] T Roelandt et al. Int J Cosmet Sci. LEKTI-1 in sickness and in health

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Keywords: KLK7/ELA2-IN-1 supplier, Elastase, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.


 
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