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TLR7/8 agonist 1 dihydrochloride

Cat. No. M10918

All AbMole products are for research use only, cannot be used for human consumption.

TLR7/8 agonist 1 dihydrochloride  Structure
Size Price Availability Quantity
5mg USD 325  USD325 In stock
10mg USD 540  USD540 In stock
25mg USD 1050  USD1050 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

TLR7/8 agonist 1 dihydrochloride is a dual agonist of toll-like receptor TLR7/TLR8.

Chemical Information
Molecular Weight 395.94
Formula C22H26ClN5
CAS Number 1620278-72-9
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Audrey Lee, et al. Nat Commun. A molecular atlas of innate immunity to adjuvanted and live attenuated vaccines, in mice

[2] Nanda Kishore Routhu, et al. Nat Commun. SARS-CoV-2 RBD trimer protein adjuvanted with Alum-3M-052 protects from SARS-CoV-2 infection and immune pathology in the lung

[3] Elizabeth A Marchant, et al. Pediatr Res. Attenuated innate immune defenses in very premature neonates during the neonatal period

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