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 About 16 results found for searched term "TLR" (0.223 seconds)

Cat.No.  Name Target
M5105 MD2-TLR4-IN-1 TLR
MD2-TLR4-IN-1 is an inhibitor of myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) complex, inhibiting lipopolysaccharides (LPS)-induced expression of tumor necrosis factor alpha (TNF-α) and interleukin-6 (IL-6) in macrophages with IC50 values of 0.89 μM and 0.53 μM, respectively.
M6246 TLR7-agonist-1 TLR
TLR7-agonist-1 is a potent and selective Toll-like Receptor 7 (TLR7) agonist with a LEC of 0.4 μM.
M9063 TLR2-IN-C29 TLR
C29
C29 is a Toll-like receptor 2 (TLR2) inhibitor. C29 blocked HTLR2/1 and HTLR2/6 with IC50 values of 19.7 and 37.6 μM, respectively.
M9651 TLR4-IN-C34 TLR
C34
C34 is a TLR4 inhibitor, which inhibited TLR4 in enterocytes and macrophages in vitro, and reduced systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis.
M10918 TLR7/8 agonist 1 dihydrochloride TLR
TLR7/8 agonist 1 dihydrochloride is a dual agonist of toll-like receptor TLR7/TLR8.
M11411 1V209 TLR
TLR7 agonist T7
1V209 (TLR7 agonist T7) is a Toll-like receptor 7 (TLR7) agonist with antitumor effects. 1V209 can be conjugated with various polysaccharides to improve their water solubility, enhance efficacy and maintain low toxicity.
M14096 TLR1 Others
TLR1 (compound 4a) is a low molecular weight, cell-penetrating Toll/IL-1 receptor/resistance (TIR) domain/BB-Loop mimic. TLR1 inhibits IL-1 receptor-mediated responses.
M27994 TLR7 agonist 3  TLR
TLR7 agonist 3 (Compound 2) is a potent agonist of toll-like receptor 7 (TLR7). TLR7 has an important role in immune activation processes and represents an emerging agent discovery target for the development of immunomodulators.
M28075 TLR7/8 agonist 1  TLR
TLR7/8 agonist 1 is a toll-like receptor (TLR7)/TLR8 dual-agonistic imidazoquinoline.
M41562 TLR7 agonist 13 Nucleoside Antimetabolite/Analog
TLR7 agonist 13 is a guanosine analog.
M42063 TLR7/8 agonist 8 TLR
TLR7/8 agonist 8 is a potent toll-like receptor 7/8 (TLR7/8) dual agonist, with EC50s of 27 and 12 nM for hTLR7 and hTLR8, respectively.
M42071 TLR7/8/9 antagonist 2 TLR
TLR7/8/9 antagonist 2 is an orally active TLR7/8/9 antagonist.
M42072 TLR8 agonist 6 TLR
TLR8 agonist 6 is a TLR8 agonist, with an EC50 of 0.052 μM.
M42073 TLR7 agonist 9 TLR
TLR7 agonist 9 is an aonist of TLR7.
M43177 C12-TLRa Others
C12-TLRa is an adjuvant lipidoid.
M53290 N-myristoyl-RKRTLRRL PKC
N-myristoyl-RKRTLRRL inhibits binding of PKC substrates.



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