About 30 results found for searched term "TLR" (0.054 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M5105 | MD2-TLR4-IN-1 | TLR |
| MD2-TLR4-IN-1 is an inhibitor of myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) complex, inhibiting lipopolysaccharides (LPS)-induced expression of tumor necrosis factor alpha (TNF-α) and interleukin-6 (IL-6) in macrophages with IC50 values of 0.89 μM and 0.53 μM, respectively. | ||
| M6246 | TLR7-agonist-1 | TLR |
| TLR7-agonist-1 is a potent and selective Toll-like Receptor 7 (TLR7) agonist with a LEC of 0.4 μM. | ||
| M9063 | TLR2-IN-C29 | TLR |
| C29 | ||
| C29 is a Toll-like receptor 2 (TLR2) inhibitor. C29 blocked HTLR2/1 and HTLR2/6 with IC50 values of 19.7 and 37.6 μM, respectively. | ||
| M9651 | TLR4-IN-C34 | TLR |
| C34 | ||
| TLR4-IN-C34 is a TLR4 inhibitor, which inhibited TLR4 in enterocytes and macrophages in vitro, and reduced systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis. | ||
| M9746 | CU-CPT-8m | TLR |
| CU-CPT8m; TLR8-specific antagonist | ||
| CU-CPT8m is an antagonist of toll-like receptor 8 (TLR8) with Kd of 220 nM and IC50 of 67 nM in assay. | ||
| M10918 | TLR7/8 agonist 1 dihydrochloride | TLR |
| TLR7/8 agonist 1 dihydrochloride is a dual agonist of toll-like receptor TLR7/TLR8. | ||
| M11411 | 1V209 | TLR |
| TLR7 agonist T7 | ||
| 1V209 (TLR7 agonist T7) is a Toll-like receptor 7 (TLR7) agonist with antitumor effects. 1V209 can be conjugated with various polysaccharides to improve their water solubility, enhance efficacy and maintain low toxicity. | ||
| M14096 | TLR1 | Others |
| TLR1 (compound 4a) is a low molecular weight, cell-penetrating Toll/IL-1 receptor/resistance (TIR) domain/BB-Loop mimic. TLR1 inhibits IL-1 receptor-mediated responses. | ||
| M27994 | TLR7 agonist 3 | TLR |
| TLR7 agonist 3 (Compound 2) is a potent agonist of toll-like receptor 7 (TLR7). TLR7 has an important role in immune activation processes and represents an emerging agent discovery target for the development of immunomodulators. | ||
| M28075 | TLR7/8 agonist 1 | TLR |
| TLR7/8 agonist 1 is a toll-like receptor (TLR7)/TLR8 dual-agonistic imidazoquinoline. | ||
| M41562 | TLR7 agonist 13 | Nucleoside Antimetabolite/Analog |
| TLR7 agonist 13 is a guanosine analog. | ||
| M42063 | TLR7/8 agonist 8 | TLR |
| TLR7/8 agonist 8 is a potent toll-like receptor 7/8 (TLR7/8) dual agonist, with EC50s of 27 and 12 nM for hTLR7 and hTLR8, respectively. | ||
| M42071 | TLR7/8/9 antagonist 2 | TLR |
| TLR7/8/9 antagonist 2 is an orally active TLR7/8/9 antagonist. | ||
| M42072 | TLR8 agonist 6 | TLR |
| TLR8 agonist 6 is a TLR8 agonist, with an EC50 of 0.052 μM. | ||
| M42073 | TLR7 agonist 9 | TLR |
| TLR7 agonist 9 is an aonist of TLR7. | ||
| M43177 | C12-TLRa | Others |
| C12-TLRa is an adjuvant lipidoid. | ||
| M53290 | N-myristoyl-RKRTLRRL | PKC |
| N-myristoyl-RKRTLRRL inhibits binding of PKC substrates. | ||
| M58146 | TLR4-IN-C34-C2-COOH | TLR |
| TLR4-IN-C34-C2-COO is a linker that incorporates TLR4 inhibitor TLR4-IN-C34. TLR4-IN-C34 inhibits TLR4 in enterocytes and macrophages, and reduces systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis. | ||
| M56406 | TLR7/8-IN-1 | TLR |
| TLR7/8-IN-1 is a crystalline from of a TLR7/TLR8 inhibitor. | ||
| M59514 | Tlr9 Mouse Pre-designed siRNA Set | siRNA |
| toll-like receptor 9 | ||
| Mouse Tlr9 Pre-designed siRNA Set contains three designed siRNAs for Tlr9 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 81897 | ||
| M60057 | TLR2 Human Pre-designed siRNA Set | siRNA |
| toll like receptor 2 | ||
| Human TLR2 Pre-designed siRNA Set contains three designed siRNAs for TLR2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 7097 | ||
| M60357 | TLR4 Human Pre-designed siRNA Set | siRNA |
| toll like receptor 4 | ||
| Human TLR4 Pre-designed siRNA Set contains three designed siRNAs for TLR4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 7099 | ||
| M60944 | TLR5 Human Pre-designed siRNA Set | siRNA |
| toll like receptor 5 | ||
| Human TLR5 Pre-designed siRNA Set contains three designed siRNAs for TLR5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 7100 | ||
| M61121 | TLR1 Human Pre-designed siRNA Set | siRNA |
| toll like receptor 1 | ||
| Human TLR1 Pre-designed siRNA Set contains three designed siRNAs for TLR1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 7096 | ||
| M61404 | TLR7 Human Pre-designed siRNA Set | siRNA |
| toll like receptor 7 | ||
| Human TLR7 Pre-designed siRNA Set contains three designed siRNAs for TLR7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 51284 | ||
| M62118 | Tlr4 Mouse Pre-designed siRNA Set | siRNA |
| toll-like receptor 4 | ||
| Mouse Tlr4 Pre-designed siRNA Set contains three designed siRNAs for Tlr4 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 21898 | ||
| M62327 | TLR3 Mouse Pre-designed siRNA Set | siRNA |
| toll-like receptor 3 | ||
| Mouse TLR3 Pre-designed siRNA Set contains three designed siRNAs for TLR3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 142980 | ||
| M62594 | TLR8 Human Pre-designed siRNA Set | siRNA |
| toll like receptor 8 | ||
| Human TLR8 Pre-designed siRNA Set contains three designed siRNAs for TLR8 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 51311 | ||
| M63475 | TLR1 Mouse Pre-designed siRNA Set | siRNA |
| toll-like receptor 1 | ||
| Mouse TLR1 Pre-designed siRNA Set contains three designed siRNAs for TLR1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 21897 | ||
| M63820 | TLR9 Human Pre-designed siRNA Set | siRNA |
| toll like receptor 9 | ||
| Human TLR9 Pre-designed siRNA Set contains three designed siRNAs for TLR9 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 54106 | ||
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