All AbMole products are for research use only, cannot be used for human consumption.
TH1020 is an effective selective toll-like receptor 5 (TLR5)/ flagellin complex antagonist with IC50 of 0.85 μM. TH1020 inhibits flagellin-induced TLR5 signal transduction, but has no effect on TLR2, TLR3, TLR4, TLR7 and TLR8.
| Molecular Weight | 453.54 |
| Formula | C23H15N7S2 |
| CAS Number | 1841460-82-9 |
| Solubility (25°C) | DMSO 2.27 mg/mL (with gentle warming) |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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