All AbMole products are for research use only, cannot be used for human consumption.
SRT 1720 is a potent activator of the human SIRT1, EC1.5 The value is 0.16 μM and simultaneously inhibits SIRT2 and SIRT3, EC1.5 The values are 37 μM and > 300 μM, respectively.
Br J Dermatol. 2024 Dec 31.
Spatial proteomics reveals sirtuin 1 to be a determinant of T-cell infiltration in human melanoma
SRT 1720 purchased from AbMole
Toxicol Appl Pharmacol. 2023 Apr 5;116509.
Suppression of SIRT1/FXR signaling pathway contributes to oleanolic acid-induced liver injury
SRT 1720 purchased from AbMole
| Molecular Weight | 469.56 |
| Formula | C25H23N7OS |
| CAS Number | 925434-55-5 |
| Solubility (25°C) | DMSO ≥ 60 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Sirtuin Products |
|---|
| SIRT1-IN-1
SIRT1-IN-1 is a selective SIRT1 inhibitor with an IC50 of 0.205 μM. |
| Sirtuin-1 inhibitor 1
Sirtuin-1 inhibitor 1 is an inhibitor of Sirtuin-1 that plays important roles in obesity-induced diabetes and aging-related diseases. |
| ADTL-SA1215
ADTL-SA1215 is a first-in-class, specific small molecule activator of SIRT3 that modulates autophagy in triple-negative breast cancer. |
| SIRT2/6-IN-1
SIRT2/6-IN-1 is a SIRT6/SIRT2 inhibitor, with IC50s of 106 μM and 114 μM. |
| SIRT6-IN-2
SIRT6-IN-2 is a selective SIRT6 inhibitor (IC50: 34 μM). |
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Products are for research use only. Not for human use. We do not sell to patients.
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