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SM-276001

Cat. No. M10704

All AbMole products are for research use only, cannot be used for human consumption.

SM-276001  Structure
Size Price Availability Quantity
5mg USD 340  USD340 In stock
10mg USD 560  USD560 In stock
50mg USD 1600  USD1600 In stock
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Quality Control & Documentation
Biological Activity

SM-276001 is a potent and selective TLR7 agonist that induces an antitumor immune response. SM-276001 is an orally active interferon (IFN) inducer.

Chemical Information
Molecular Weight 327.38
Formula C16H21N7O
CAS Number 473930-22-2
Form Solid
Solubility (25°C) DMSO ≥ 100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Erina Koga-Yamakawa, et al. Int J Cancer. Intratracheal and oral administration of SM-276001: a selective TLR7 agonist, leads to antitumor efficacy in primary and metastatic models of cancer

[2] Yoshiaki Isobe, et al. J Med Chem. Synthesis and biological evaluation of novel 9-substituted-8-hydroxyadenine derivatives as potent interferon inducers

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Keywords: SM-276001 supplier, TLR, inhibitors, activators

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