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Rifabutin (Mycobutin) is a semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits bacterial DNA-dependent RNA polymerase, thereby suppressing the initiation of RNA formation and leading to inhibition of RNA synthesis and transcription. [1, 2]
| Molecular Weight | 847 |
| Formula | C46H62N4O11 |
| CAS Number | 72559-06-9 |
| Form | Solid |
| Solubility (25°C) | DMSO 50 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Daniel Schfle, et al. Rifabutin Is Inactivated by Mycobacterium abscessus Arr
[3] Yoann Crabol, et al. Rifabutin: where do we stand in 2016?
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