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Rifabutin

Cat. No. M3387

All AbMole products are for research use only, cannot be used for human consumption.

Rifabutin Structure
Synonym:

Ansamycin; LM-427

Size Price Availability Quantity
10mg USD 30 In stock
25mg USD 40 In stock
50mg USD 63 In stock
100mg USD 90 In stock
200mg USD 135 In stock
500mg USD 225 In stock
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Quality Control & Documentation
Biological Activity

Rifabutin (Mycobutin) is a semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits bacterial DNA-dependent RNA polymerase, thereby suppressing the initiation of RNA formation and leading to inhibition of RNA synthesis and transcription. [1, 2]

Chemical Information
Molecular Weight 847
Formula C46H62N4O11
CAS Number 72559-06-9
Form Solid
Solubility (25°C) DMSO 50 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Vincent Trebosc, et al. Rifabutin for infusion (BV100) for the treatment of severe carbapenem-resistant Acinetobacter baumannii infections

[2] Daniel Schfle, et al. Rifabutin Is Inactivated by Mycobacterium abscessus Arr

[3] Yoann Crabol, et al. Rifabutin: where do we stand in 2016?

[4] No authors listed. Tuberculosis (Edinb). Rifabutin

[5] A L Tseng, et al. Rifabutin-associated uveitis

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Keywords: Rifabutin, Ansamycin; LM-427 supplier, Antibiotic, inhibitors, activators

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