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Nesfatin is a metabolic polypeptide and is the N-terminal region of the precursor protein, Nucleobindin2 (encoded by NUCB2 gene). Nesfatin-1 is a naturally occurring protein and originally identified as a hypothalamic neuropeptide. Additionally, Nesfatin can be found in other areas of brain, and in pancreatic isletsβ-cells, gastric endocrine cells and adipocytes. It is responsible for regulating appetite and production of body fat. A lack of nesfatin-1 in the brain leads to an increase of appetite, more frequent episodes of hunger, an increase of body fat and weight, and the inability to 'feel full'.
Recombinant Human Nesfatin-1 expressed the target gene encoding Val25-Leu106.
Accession: P80303
Endotoxin < 1 EU/µg
Apparent Molecular Weight: 10 KDa, reducing conditions
Lyophilized from a 0.2 μm filtered solution of 10mM Sodium Phosphate, pH 6.5.
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in distilled water up to 100 μg/ml. |
| Storage | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
[5] Jing-Jing Luo, et al. Clin Chim Acta. Nesfatin-1 in lipid metabolism and lipid-related diseases
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