| Cat.No. | Name | Information |
|---|---|---|
| M58628 | Recombinant Mouse Progranulin Protein (HEK293, C-His) | Progranulin (PGRN) proteins regulate lysosomal function, affecting protein transport, enzymatic activity, and acidification. It degrades mature cathepsin D via cathepsin B. The precursor protein, progranulin, is also called Proepithelin and PC cell-derived growth factor. Granulin family members are important in normal development, wound healing, and tumorigenesis. Granulins have possible cytokine-like activity. |
| M55397 | Recombinant Human HMGB1 Protein (E. coli) | High mobility group protein B1 is a member of the HMGB family consisting of three members, HMGB1, HMGB2 and HMGB3. As a nuclear protein, HMGB1 stabilizes nucleosomes and allows bending of DNA that facilitates gene transcription which is essential for individual survival. Meanwhile, it is revealed that HMGB1 can also act as a cytokine extracellularlly and regulates monocyte, T cell, dendritic cell activities in inflammatory responses. |
| M40767 | Recombinant Mouse MFGE8 Protein (HEK293, C-6×His) | Mouse MFGE8 Protein contributes to phagocytic removal of apoptotic cells in many tissues. It plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. |
| M40758 | Recombinant Human MFGE8 Protein (Baculovirus-Insect, His-AVI, Biotinylated) | MFG-E8 is expressed in mammary epithelial cell surfaces and aortic media. MFG-E8 has opsonization of the apoptotic cells and binding to integrins on the surface of phagocytic cells. It also mediates the engulfment of the dead cell. |
| M22497 | Recombinant Human HMGB1 Protein (E. coli, C-His) | Human High-mobility group box 1 protein (HMGB1), previously known as HMG-1 or amphoterin, is a member of the high mobility group box family of non-histone chromosomal proteins. Human HMGB1 is expressed as a 30 kDa, 215 amino acid (a.a.) single chain polypeptide. |
| M22496 | Recombinant Mouse HMGB1 Protein (E. coli, C-His) | The recombinant mouse HMGB1/Fc is a disulfide-linked homodimer. High-mobility group box 1 protein (HMGB1), also known as HMG-1 or amphoterin previously, is a member of the HMGB family. HMGB1 is a DNA-binding nuclear protein, released actively following cytokine stimulation as well as passively during cell death. |
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