Recombinant human Apolipoprotein H(APOH) protein (HEK293, His) was expressed in HEK293 cells with a His tag on the N-terminal. Apolipoprotein H is the primary target of antiphospholipid antibodies (aPLs) found in many patients with systemic lupus erythematosus and antiphospholipid syndrome (APS).
| Solubility (25°C) | It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O or PBS. |
| Storage | -20°C |
| Species | Mouse | Rat | Rabbit | Guinea pig | Hamster | Dog |
| Weight (kg) | 0.02 | 0.15 | 1.8 | 0.4 | 0.08 | 10 |
| Body Surface Area (m2) | 0.007 | 0.025 | 0.15 | 0.05 | 0.02 | 0.5 |
| Km factor | 3 | 6 | 12 | 8 | 5 | 20 |
| Animal A (mg/kg) = Animal B (mg/kg) multiplied by | Animal B Km |
| Animal A Km |
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
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| Recombinant Human USP14 (E.coli, N-6His)
USP14 belongs to the ubiquitin-specific processing (USP) family which is a deubiquitinating enzyme (DUB) with His and Cys domains. USP14 acts also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. |
| Recombinant Human EpCAM/Trop-1 (Mammalian, C-Fc)
Epithelial Cell Adhesion Molecule (EpCAM) is a signal type I transmembrane glycoprotein. EpCAM plays a role in embryonic stem cells proliferation and differentiation; it up-regulates the expression of FABP5, MYC and Cyclin A and Cyclin E. It is highly and selectively expressed by undifferentiated embryonic stem cells. |
| Recombinant Human IL-36 gamma/IL-1 F9 Protein (E. coli, aa 18-169, His Tag)
The recombinant human IL1F9 consists of 168 amino acids and predicts a molecular mass of 19.1 KDa. A DNA sequence encoding the mature form of human IL1F9 (Ser18-Asp169) was expressed with a polyhistide tag at the N-terminus. |
| Recombinant Human IL-36 gamma/IL-1 F9 Protein (E. coli)
The recombinant human IL1F9 consisting of 169 amino acids and has a calculated molecular mass of 18.9 kDa. A DNA sequence encoding the human IL-1F9 isoform 1 (Met 1-Asp 169) was expressed. |
| Recombinant Human APOL1 Protein (Baculovirus-Insect, C-His)
APOL1, also known as apolipoprotein L1, belongs to the apolipoprotein L family. It may play a role in lipid exchange and transport throughout the body. |
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