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PKF050-638 

Cat. No. M30245

All AbMole products are for research use only, cannot be used for human consumption.

PKF050-638  Structure

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Quality Control & Documentation
Biological Activity

PKF050-638 is a potent and selective inhibitor of HIV-1 Rev (IC50=0.04 μM). PKF050-638 inhibits the CRM1-mediated Rev nuclear export by disrupting CRM1-NES interaction.

Chemical Information
Molecular Weight 292.72
Formula C13H13ClN4O2
CAS Number 528893-52-9
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Giovanni Luca Gravina, et al. J Hematol Oncol. Nucleo-cytoplasmic transport as a therapeutic target of cancer

[2] Dirk Daelemans, et al. Proc Natl Acad Sci U S A. A synthetic HIV-1 Rev inhibitor interfering with the CRM1-mediated nuclear export

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  Catalog
Abmole Inhibitor Catalog




Keywords: PKF050-638  supplier, HIV Protease, inhibitors, activators

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