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PDK4-IN-1 hydrochloride is an anthraquinone derivative and a potent and orally active pyruvate dehydrogenase kinase 4 (PDK4) inhibitor with an IC50 value of 84 nM. PDK4-IN-1 hydrochloride potently represses cellular transformation and cellular proliferation and induces apoptosis. PDK4-IN-1 hydrochloride has antidiabetic, anticancer and anti-allergic activity.
| Molecular Weight | 393.87 |
| Formula | C22H20ClN3O2 |
| CAS Number | 2310262-11-2 |
| Solubility (25°C) | DMSO ≥ 90 mg/mL |
| Storage | 2-8°C, dry, sealed |
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