Certificate of Analysis


Product Name: PDK4-IN-1 hydrochloride
Catalog Number: M21648
CAS Number: 2310262-11-2

Physical and Chemical Properties
Formula: C22H20ClN3O2
Molecular Weight: 393.87
Solubility: DMSO ≥ 90 mg/mL
Storage: 2-8°C, dry, sealed
Chemical Structure: PDK4-IN-1 hydrochloride Structure
Analytical Data
QC Standard: 99.68%
H-NMR: Consistent with structure
Product Information
Description: PDK4-IN-1 hydrochloride is an anthraquinone derivative and a potent and orally active pyruvate dehydrogenase kinase 4 (PDK4) inhibitor with an IC50 value of 84 nM. PDK4-IN-1 hydrochloride potently represses cellular transformation and cellular proliferation and induces apoptosis.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.