All AbMole products are for research use only, cannot be used for human consumption.
PBIT is a JARID1 (Jumonji AT-Rich Interactive Domain 1) inhibitor with IC50 values of 3, 4.9 and 6 μM for JARID1B, 1A and 1C, respectively. It can increase trimethylation of H3K4 in HeLa cells and block the proliferation of tumor cells expressing high levels of JARID1B.
| Molecular Weight | 241.31 |
| Formula | C14H11NOS |
| CAS Number | 2514-30-9 |
| Solubility (25°C) | DMSO ≥ 40 mg/mL |
| Storage | 2-8°C |
| Related Histone demethylase Products |
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| JMJD6-IN-1
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