All AbMole products are for research use only, cannot be used for human consumption.
PBIT is a JARID1 (Jumonji AT-Rich Interactive Domain 1) inhibitor with IC50 values of 3, 4.9 and 6 μM for JARID1B, 1A and 1C, respectively. It can increase trimethylation of H3K4 in HeLa cells and block the proliferation of tumor cells expressing high levels of JARID1B.
| Molecular Weight | 241.31 |
| Formula | C14H11NOS |
| CAS Number | 2514-30-9 |
| Solubility (25°C) | DMSO ≥ 40 mg/mL |
| Storage | 2-8°C |
| Related Histone demethylase Products |
|---|
| PFI-90
PFI-90 is a selective inhibitor of histone demethylase (KDM3B) that inhibits PAX3-FOXO1 action. |
| CPI-4203
CPI-4203 is a potent KDM5A inhibitor with an IC50 of 250 nM. |
| KDM2B-IN-4
KDM2B-IN-4 is a histone demethylase KDM2B inhibitor. |
| Zavondemstat
Zavondemstat (QC8222; TACH 101) is an inhibitor of histone lysine demethylase 4D (KDM4D) with antineoplastic activity. |
| Zavondemstat L-lysine
Zavondemstat (QC8222; TACH 101) (L-lysine) is an inhibitor of histone lysine demethylase 4D (KDM4D) with antineoplastic activity. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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