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Okanin

Cat. No. M10223

All AbMole products are for research use only, cannot be used for human consumption.

Okanin Structure
Size Price Availability Quantity
5mg USD 300  USD300 In stock
10mg USD 400  USD400 In stock
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Quality Control & Documentation
Biological Activity

Okanin attenuates LPS-induced microglial activation through inhibition of the TLR4/NF-κB signaling pathways, it is the effective constituent of the flower tea Coreopsis tinctoria. Okanin shows significant activities on both linoleic acid peroxidation inhibition and DPPH radical scavenging effect.

Chemical Information
Molecular Weight 288.25
Formula C15H12O6
CAS Number 484-76-4
Solubility (25°C) DMSO ≥ 10 mg/mL
Storage 2-8°C, protect from light, dry, sealed
References

[1] Yurui Shi, et al. J Anal Methods Chem. Determination and Pharmacokinetics of Okanin in Rat Plasma by UltraHigh Performance Liquid Chromatography Coupled with Triple-Quadrupole Tandem Mass Spectrometry

[2] Yue Hou, et al. Sci Rep. Okanin, effective constituent of the flower tea Coreopsis tinctoria, attenuates LPS-induced microglial activation through inhibition of the TLR4/NF-κB signaling pathways

[3] Jin-Sang Kil, et al. J Clin Biochem Nutr. Okanin, a chalcone found in the genus Bidens, and 3-penten-2-one inhibit inducible nitric oxide synthase expression via heme oxygenase-1 induction in RAW264.7 macrophages activated with lipopolysaccharide

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