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NSC348884

Cat. No. M9477

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NSC348884 Structure
Size Price Availability Quantity
5mg USD 65  USD65 In stock
10mg USD 120  USD120 In stock
25mg USD 230  USD230 In stock
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Quality Control & Documentation
Biological Activity

NSC348884 is a nucleophosmin (NPM) inhibitor that also disrupts oligomer formation as well as induces apoptosis, with an IC50 of 1.7-4.0 μM for inhibition of proliferation in different cancer cell lines.Can be used in cancer-related studies.

Chemical Information
Molecular Weight 636.79
Formula C38H40N10
CAS Number 81624-55-7
Solubility (25°C) DMSO ≥ 27 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Zhang J, et al. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. [Inhibitory effect of NSC348884, a small molecular inhibitor of nucleophosmin, on the growth of hepatocellular carcinoma cell line hepG2].

[2] Qi W, et al. Oncogene. NSC348884, a nucleophosmin inhibitor disrupts oligomer formation and induces apoptosis in human cancer cells.

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Keywords: NSC348884 supplier, Apoptosis, inhibitors, activators

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