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Azemiglitazone

Cat. No. M5748

All AbMole products are for research use only, cannot be used for human consumption.

Azemiglitazone Structure
Synonym:

MSDC-0602; MSDC0602

Size Price Availability Quantity
Free Sample (0.5-1 mg)  USD 0 In stock
10mM*1mL in DMSO USD 62  USD62 In stock
1mg USD 24  USD24 In stock
5mg USD 58  USD58 In stock
10mg USD 88  USD88 In stock
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Quality Control & Documentation
Biological Activity

Azemiglitazone (MSDC-0602) is a PPARγ -retained thiazolidindione (TZD) that interacts with mitochondrial pyruvate vector (MPC) and inhibits its activity.

Chemical Information
Molecular Weight 371.41
Formula C19H17NO5S
CAS Number 1133819-87-0
Solubility (25°C) DMSO 100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Patrick A Vigueira, et al. Exp Physiol. The beneficial metabolic effects of insulin sensitizers are not attenuated by mitochondrial pyruvate carrier 2 hypomorphism

[2] Kyle S McCommis, et al. Hepatology. Targeting the mitochondrial pyruvate carrier attenuates fibrosis in a mouse model of nonalcoholic steatohepatitis

[3] Zhouji Chen, et al. J Biol Chem. Insulin resistance and metabolic derangements in obese mice are ameliorated by a novel peroxisome proliferator-activated receptor γ-sparing thiazolidinedione

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Keywords: Azemiglitazone, MSDC-0602; MSDC0602 supplier, PPAR, inhibitors, activators

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