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Metformin

Cat. No. M3244

All AbMole products are for research use only, cannot be used for human consumption.

Metformin Structure
Synonym:

1,1-Dimethylbiguanide

Size Price Availability Quantity
Free Sample (0.1-0.5 mg)  USD 0 In stock
5mg USD 30  USD30 In stock
10mg USD 40  USD40 In stock
25mg USD 60  USD60 In stock
50mg USD 80  USD80 In stock
100mg USD 100  USD100 In stock
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Quality Control & Documentation
Biological Activity

Metformin (1, 1-dimethylbiguanide) inhibits mitochondrial respiratory chains in the liver, leads to AMPK activation and enhances insulin sensitivity, and can be used in type 2 diabetes research. Metformin can cross the blood-brain barrier and induce autophagy, and Metformin is a CD47 inhibitor in vitro.

Product Citations
Chemical Information
Molecular Weight 129.17
Formula C4H11N5
CAS Number 657-24-9
Solubility (25°C) DMSO 60 mg/mL
Water 30 mg/mL
Storage -20°C, sealed, protect from light
References

[1] Ziquan Lv, et al. Metformin and Its Benefits for Various Diseases

[2] Monika Podhorecka, et al. Metformin - its potential anti-cancer and anti-aging effects

[3] Laura J McCreight, et al. Metformin and the gastrointestinal tract

[4] Ralph DeFronzo, et al. Metformin-associated lactic acidosis: Current perspectives on causes and risk

[5] Yanqun Liu, et al. Neuroinflammation . Metformin attenuates blood-brain barrier disruption in mice following middle cerebral artery occlusion

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Keywords: Metformin, 1,1-Dimethylbiguanide supplier, AMPK, inhibitors, activators

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