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Cat. No. M13493
Mebendazole Structure
Size Price Availability Quantity
500mg USD 55  USD55 In stock
1g USD 65  USD65 In stock
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Quality Control & Documentation
Biological Activity

Mebendazole is a highly effective, broad-spectrum antihelmintic indicated for the treatment of nematode infestations; has been found as a hedgehog inhibitor.

Chemical Information
Molecular Weight 295.29
Formula C16H13N3O3
CAS Number 31431-39-7
Form Solid
Solubility (25°C) DMSO 4.17 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.


[1] R Caete, et al. Trans R Soc Trop Med Hyg. Mebendazole in parasitic infections other than those caused by soil-transmitted helminths

[2] U Junge, et al. Z Gastroenterol. [Mebendazole-hepatitis]

[3] H T Goodman. Med J Aust. Mebendazole

[4] T C Beard. Med J Aust. Mebendazole

[5] J S Keystone, et al. Ann Intern Med. Mebendazole

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Keywords: Mebendazole supplier, TNIK, inhibitors, activators

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