TNIK Traf2 and Nck-Interacting Kinase

Cat.No.	Name	Information
M16102	Jatrorrhizine	Jatrorrhizine, an isoquinoline alkaloid found in common medicinal plants, is also a TNIK inhibitor with antibacterial, anti-inflammatory and antitumor activities.
M13493	Mebendazole	Mebendazole is a highly effective, broad-spectrum antihelmintic indicated for the treatment of nematode infestations; has been found as a hedgehog inhibitor.
M5279	NCB-0846	NCB-0846 is a novel, orally small-molecule Wnt inhibitor that inhibits TNIK (TRAF2 and NCK-Interacting Kinase) with an IC50 value of 21 nM.
M49491	TNIK-IN-3	TNIK-IN-3 is a potent, selective and orally active TNIK inhibitor with an IC50 value of 0.026 μM. In addition, TNIK-IN-3 inhibits Flt4 (IC50=0.030 μM), Flt1 (IC50=0.191 μM) and DRAK1 (IC50=0.411 μM). -3 can be used in studies related to colorectal cancer.
M31148	PF-794	PF-794 (PF-06279794) is a potent, selective, ATP-competitive TNIK inhibitor.