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TNIK-IN-3 is a potent, selective and orally active TNIK inhibitor with an IC50 value of 0.026 μM. In addition, TNIK-IN-3 inhibits Flt4 (IC50=0.030 μM), Flt1 (IC50=0.191 μM) and DRAK1 (IC50=0.411 μM). -3 can be used in studies related to colorectal cancer.
| Molecular Weight | 387.41 |
| Formula | C23H18FN3O2 |
| CAS Number | 2754265-25-1 |
| Form | Solid |
| Solubility (25°C) | DMSO 83.33 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related TNIK Products |
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| PF-794
PF-794 (PF-06279794) is a potent, selective, ATP-competitive TNIK inhibitor. |
| Jatrorrhizine
Jatrorrhizine, an isoquinoline alkaloid found in common medicinal plants, is also a TNIK inhibitor with antibacterial, anti-inflammatory and antitumor activities. |
| Mebendazole
Mebendazole is a highly effective, broad-spectrum antihelmintic indicated for the treatment of nematode infestations; has been found as a hedgehog inhibitor. |
| NCB-0846
NCB-0846 is a novel, orally small-molecule Wnt inhibitor that inhibits TNIK (TRAF2 and NCK-Interacting Kinase) with an IC50 value of 21 nM. |
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Products are for research use only. Not for human use. We do not sell to patients.
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