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LRRK2-IN-8

Cat. No. M49509

All AbMole products are for research use only, cannot be used for human consumption.

LRRK2-IN-8 Structure

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Quality Control & Documentation
Biological Activity

LRRK2-IN-8 is a LRRK2 inhibitor.

Chemical Information
Molecular Weight 326.3
Formula C16H12F2N6
CAS Number 2770269-44-6
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
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LRRK2/NUAK1/TYK2-IN-1 (conpound 226) shows inhibitory activity toward LRRK2 (Wt), LRRK2 (G2019), TYK2 and NUAK1, with IC50 values lower than 10 nM.

EB-42486

EB-42486 is a novel potent and highly selective inhibitor of G2019S-LRRK2 (IC50 < 0.2 nM).

CZC-54252

CZC-54252 is a potent and selective LRRK2 inhibitor with IC50s of 1.28 nM and 1.85 nM for human wild type LRRK2 and G2019S LRRK2, respectively.

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HG-10-102-01 is a potent and selective inhibitor of wild-type LRRK2(IC50=23.3 nM) and the G2019S mutant(IC50=3.2 nM).

  Catalog
Abmole Inhibitor Catalog




Keywords: LRRK2-IN-8 supplier, LRRK2, inhibitors, activators

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