Inhibitors
Cat.No. | Name | Information |
---|---|---|
M10595 | MLi-2 | MLi-2 is a highly potent, and selective LRRK2 kinase inhibitor with central nervous system activity. MLi-2 exhibits exceptional potency in a purified LRRK2 kinase assay in vitro (IC50 = 0.76 nM), a cellular assay monitoring dephosphorylation of LRRK2 pSer935 LRRK2 (IC50 = 1.4 nM), and a radioligand competition binding assay (IC50 = 3.4 nM). |
M10452 | PFE-360 | PFE-360, also known as PF-06685360, is a potent and selective, brain penetrated inhibitor of LRRK2 kinase. |
M6649 | CZC 25146 | CZC 25146 is a potent LRRK2 inhibitor. |
M5204 | JH-II-127 | JH-II-127 is a highly selective LRRK2 inhibitor with an IC50 = 6.5 nM. |
M4949 | LRRK2-IN-1 | LRRK2-IN-1 is useful in treatment of Parkinson's disease. |
M4831 | GSK2578215A | GSK2578215A is a potent and selective LRRK2 kinase inhibitor with IC50 of 8.9 nM and 10.9 nM for LRRK2 (G2019S) and LRRK2 (WT), respectively. |
M3929 | PF-06447475 | PF-06447475 is a highly potent, selective, brain penetrant LRRK2 inhibitor with IC0 of 3 nM/11 nM for Wt LRRK2/G2019S LRRK2 respectively. |
M3795 | GNE-9605 | GNE-9605 is a highly potent, selective, and brain-penetrant LRRK2 inhibitor with IC50 of 19 nM. |
M3649 | GNE-7915 | GNE-7915 is a highly potent, selective, and brain-penetrable leucine-rich repeat kinase 2 (LRRK2) inhibitor with IC50 and Ki of 9 nM and 1 nM, respectively. |
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2020 AbMole BioScience. All Rights Reserved.