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GNE-7915 tosylate is a potent, selective and brain-penetrant inhibitor of LRRK2 with an IC50 of 9 nM.
| Molecular Weight | 615.6 |
| CAS Number | 2070015-00-6 |
| Solubility (25°C) | DMSO ≥ 50 mg/mL |
| Storage | 2-8°C, dry, sealed |
| Related LRRK2 Products |
|---|
| LRRK2-IN-8
LRRK2-IN-8 is a LRRK2 inhibitor. |
| LRRK2/NUAK1/TYK2-IN-1
LRRK2/NUAK1/TYK2-IN-1 (conpound 226) shows inhibitory activity toward LRRK2 (Wt), LRRK2 (G2019), TYK2 and NUAK1, with IC50 values lower than 10 nM. |
| EB-42486
EB-42486 is a novel potent and highly selective inhibitor of G2019S-LRRK2 (IC50 < 0.2 nM). |
| CZC-54252
CZC-54252 is a potent and selective LRRK2 inhibitor with IC50s of 1.28 nM and 1.85 nM for human wild type LRRK2 and G2019S LRRK2, respectively. |
| WAY-333491
WAY-333491 is a LRRK2 kinase inhibitor. |
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