About 6 results found for searched term "LRRK2-IN-8" (0.128 seconds)
Cat.No. | Name | Target |
---|---|---|
M49509 | LRRK2-IN-8 | LRRK2 |
LRRK2-IN-8 is a LRRK2 inhibitor. | ||
M4831 | GSK2578215A | LRRK2 |
GSK2578215A is a potent and selective LRRK2 kinase inhibitor with IC50 of 8.9 nM and 10.9 nM for LRRK2 (G2019S) and LRRK2 (WT), respectively. | ||
M6649 | CZC-25146 | LRRK2 |
CZC25146 | ||
CZC 25146 is a potent and orally active LRRK2 inhibitor with IC50 values of 4.76 nM and 6.87 nM for wild-type LRRK2 and G2019S LRRK2, respectively. CZC-25146 inhibits PLK4, GAK, TNK1, CAMKK2 and PIP4K2C as well. | ||
M8313 | CZC-25146 hydrochloride | LRRK2 |
CZC-25146 is a potent selective and metabolically stable inhibitor of leucine-rich repeat kinase-2 (LRRK2) also known as dardarin or PARK8, a kinase with mutations linked to Parkinson’s disease. | ||
M20669 | CZC-54252 | LRRK2 |
CZC-54252 is a potent and selective LRRK2 inhibitor with IC50s of 1.28 nM and 1.85 nM for human wild type LRRK2 and G2019S LRRK2, respectively. | ||
M58400 | CZC-54252 hydrochloride | LRRK2 |
CZC-54252 HCl | ||
CZC-54252 hydrochloride is a potent and selective LRRK2 inhibitor with IC50s of 1.28 nM and 1.85 nM for wild-type and G2019S LRRK2, respectively. |
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