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LFF571

Cat. No. M3681

All AbMole products are for research use only, cannot be used for human consumption.

LFF571 Structure
Size Price Availability
10mg USD 350  USD350 Out of stock
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Quality Control & Documentation
Biological Activity

LFF571 is a compound used to treat infection with Clostridium difficile. LFF571 was used to detect 50 C. difficile and 630 anaerobic and aerobic organisms of other intestinal origin by high affinity binding to protein synthesis elongation factor Tu, fidamycin and 10 antimicrobial agents to inhibit bacterial growth. LFF571 showed strong activity against Clostridium difficile and most gram-positive anaerobic bacteria (MIC90, ≤0.25 μg/ mL), except bifidobacterium and Lactobacillus.

Chemical Information
Molecular Weight 1366.61
Formula C60H63N13O13S6
CAS Number 1160959-55-6
Solubility (25°C) DMSO
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Leeds JA1, et al. Antimicrob Agents Chemother. Mechanism of action of and mechanism of reduced susceptibility to the novel anti-Clostridium difficile compound LFF571.

[2] Trzasko A, et al. Antimicrob Agents Chemother. Efficacy of LFF571 in a hamster model of Clostridium difficile infection.

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