All AbMole products are for research use only, cannot be used for human consumption.
LE135 is an effective RAR antagonist, which can selectively bind RARα (Ki is 1.4 μM) and RARβ (Ki is 220 nM), and has a higher affinity for RARβ. The LE135 is highly selective for RARγ, RXRα, RXRβ and RXRγ. LE135 is also a vitamin A acid receptor antagonist.
| Molecular Weight | 438.56 |
| Formula | C29H30N2O2 |
| CAS Number | 155877-83-1 |
| Solubility (25°C) | DMSO ≥ 40 mg/mL |
| Storage | 2-8°C |
[5] H Umemiya, et al. Yakugaku Zasshi. [Retinoid antagonists]
| Related RAR/RXR Products |
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| AGN 196996
AGN 196996 is a potent and selective RARα antagonist with Ki value of 2 nM; little binding affinity for RARβ(Ki=1087 nM) and RARγ(Ki=8523 nM). |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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