Certificate of Analysis
| Product Name: | LE135 |
| Catalog Number: | M13345 |
| CAS Number: | 155877-83-1 |
Physical and Chemical Properties
| Formula: | C29H30N2O2 |
| Molecular Weight: | 438.56 |
| Solubility: | DMSO ≥ 40 mg/mL |
| Storage: | 2-8°C |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | LE135 is an effective RAR antagonist, which can selectively bind RARα (Ki is 1.4 μM) and RARβ (Ki is 220 nM), and has a higher affinity for RARβ. The LE135 is highly selective for RARγ, RXRα, RXRβ and RXRγ. LE135 is also a vitamin A acid receptor antagonist. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |