Free shipping on all orders over $ 500

JMS-17-2

Cat. No. M9653

All AbMole products are for research use only, cannot be used for human consumption.

JMS-17-2 Structure
Size Price Availability Quantity
1mg USD 35  USD35 In stock
5mg USD 80  USD80 In stock
10mg USD 135  USD135 In stock
50mg USD 370  USD370 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

JMS-17-2 is a potent and selective CX3CR1 antagonist with IC50 of 0.32 nM. JMS-17-2 can impairs metastatic seeding and colonization of breast cancer cells.

In vivo, JMS-17-2 (10 mg/kg; i.p.; twice a day for three weeks) causes a dramatic reduction of tumors in both skeleton and visceral organs in SCID mice.

Chemical Information
Molecular Weight 419.95
Formula C25H26ClN3O
CAS Number 1380392-05-1
Solubility (25°C) DMSO ≥ 10 mg/mL
Storage 2-8°C, protect from light, dry, sealed
References

[1] Fei Shen, et al. Mol Cancer Res. Novel Small-Molecule CX3CR1 Antagonist Impairs Metastatic Seeding and Colonization of Breast Cancer Cells

Related CXCR Products
Elubrixin

Elubrixin (SB-656933) is a potent, selective, competitive, reversible and orally active CXCR2 antagonist and an IL-8 receptor antagonist.

VUF 11222 

VUF 11222 is a CXCR3 non-peptide-like agonist.

(±)-AMG 487 

(±)-AMG 487 is a racemate of AMG 487.

Elubrixin tosylate

Elubrixin tosylate (SB-656933 tosylate) is a potent, selective, competitive, reversible and orally active CXCR2 antagonist and an IL-8 receptor antagonist.

Elubrixin hydrochloride

Elubrixin (SB-656933) hydrochloride is a potent, selective, competitive, reversible and orally active CXCR2 antagonist and an IL-8 receptor antagonist.

  Catalog
Abmole Inhibitor Catalog




Keywords: JMS-17-2 supplier, CXCR, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.