About 8 results found for searched term "CXCR" (0.067 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M13940 | CXCR2-IN-1 | CXCR |
| CXCR2-IN-1 is a central nervous system penetrant CXCR2 antagonist with a pIC50 of 9.3. | ||
| M13941 | CXCR2-IN-2 | CXCR |
| CXCR2-IN-2 is a selective, brain penetrant, and orally bioavailable CXCR2 antagonist (IC50=5.2 nM/1 nM in β-arrestin assay/CXCR2 Tango assay, respectively). | ||
| M24637 | Ulocuplumab | CXCR |
| BMS 936564; MDX 1338; Anti-Human CXCR4 Recombinant Antibody | ||
| Ulocuplumab (Anti-Human CXCR4 Recombinant Antibody/BMS-936564/MDX1338) is a fully human IgG4 anti-CXCR4 antibody. Ulocuplumab induces apoptosis and inhibits CXCL12 mediated CXCR4 activation-migration of chronic lymphocytic leukemia (CLL). Ulocuplumab exhibits antitumor activity in established tumors including acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL), and multiple myeloma xenograft models. | ||
| M28679 | CXCR7 antagonist-1 | CXCR |
| CXCR7 antagonist-1 is a CXCR7 antagonist that inhibits the binding of the SDF-1 chemokine (also known as the CXCL12 chemokine) or I-TAC (also known as CXCL11) to the chemokine receptor CXCR7. CXCR7 antagonist-1 is useful in preventing tumor cell proliferation, tumor formation, inflammatory diseases, and many other diseases. | ||
| M31027 | CXCR7 antagonist-1 hydrochloride | CXCR |
| CXCR7 antagonist-1 hydrochloride is a CXCR7 antagonist that inhibits the binding of the SDF-1 chemokine (also known as the CXCL12 chemokine) or I-TAC (also known as CXCL11) to the chemokine receptor CXCR7. CXCR7 antagonist-1 hydrochloride is useful in the research of preventing tumor cell proliferation, tumor formation, inflammatory diseases, and many other diseases. | ||
| M41799 | CXCR4-IN-1 | CXCR |
| CXCR4-IN-1 is a CXCR4 inhibitor (IC50: 20 nM). | ||
| M41801 | DOTA-CXCR4-L | CXCR |
| DOTA-CXCR4-L is a CXCR4 targeting peptide. | ||
| M53208 | CXCR4 antagonist 4 | CXCR |
| CXCR4 antagonist 4 is a potent, orally active CXCR4 antagonist (IC50=24 nM) with diminished CYP 2D6 activity, improved PAMPA permeability, potent inhibition of human immunodeficiency virus entry (IC50=7 nM). | ||
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