About 17 results found for searched term "CXCR" (0.071 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M13940 | CXCR2-IN-1 | CXCR |
| CXCR2-IN-1 is a central nervous system penetrant CXCR2 antagonist with a pIC50 of 9.3. | ||
| M13941 | CXCR2-IN-2 | CXCR |
| CXCR2-IN-2 is a selective, brain penetrant, and orally bioavailable CXCR2 antagonist (IC50=5.2 nM/1 nM in β-arrestin assay/CXCR2 Tango assay, respectively). | ||
| M24637 | Ulocuplumab | CXCR |
| BMS 936564; MDX 1338 | ||
| Ulocuplumab (Anti-Human CXCR4 Recombinant Antibody/BMS-936564/MDX1338) is a fully human IgG4 anti-CXCR4 antibody. Ulocuplumab induces apoptosis and inhibits CXCL12 mediated CXCR4 activation-migration of chronic lymphocytic leukemia (CLL). Ulocuplumab exhibits antitumor activity in established tumors including acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL), and multiple myeloma xenograft models. | ||
| M28679 | CXCR7 antagonist-1 | CXCR |
| CXCR7 antagonist-1 is a CXCR7 antagonist that inhibits the binding of the SDF-1 chemokine (also known as the CXCL12 chemokine) or I-TAC (also known as CXCL11) to the chemokine receptor CXCR7. CXCR7 antagonist-1 is useful in preventing tumor cell proliferation, tumor formation, inflammatory diseases, and many other diseases. | ||
| M31027 | CXCR7 antagonist-1 hydrochloride | CXCR |
| CXCR7 antagonist-1 hydrochloride is a CXCR7 antagonist that inhibits the binding of the SDF-1 chemokine (also known as the CXCL12 chemokine) or I-TAC (also known as CXCL11) to the chemokine receptor CXCR7. CXCR7 antagonist-1 hydrochloride is useful in the research of preventing tumor cell proliferation, tumor formation, inflammatory diseases, and many other diseases. | ||
| M41799 | CXCR4-IN-1 | CXCR |
| CXCR4-IN-1 is a CXCR4 inhibitor (IC50: 20 nM). | ||
| M41801 | DOTA-CXCR4-L | CXCR |
| DOTA-CXCR4-L is a CXCR4 targeting peptide. | ||
| M53208 | CXCR4 antagonist 4 | CXCR |
| CXCR4 antagonist 4 is a potent, orally active CXCR4 antagonist (IC50=24 nM) with diminished CYP 2D6 activity, improved PAMPA permeability, potent inhibition of human immunodeficiency virus entry (IC50=7 nM). | ||
| M59114 | Recombinant Human CXCR4 (HEK293, N-Fc) | Receptor Proteins |
| C-X-C Chemokine Receptor Type 4 | ||
| CXCR4 is an alpha-chemokine receptor specific for stromal-derived-factor-1 (SDF-1 also called CXCL12), a molecule endowed with potent chemotactic activity for lymphocytes. CXCR4 plays a role in both physiological and pathological conditions and it represents a crucial target in drug development. | ||
| M59105 | Ulocuplumab-MMAE | Antibody-Drug Conjugates (ADCs) |
| Ulocuplumab-MMAE is an antibody-drug conjugate (ADC). | ||
| M59814 | cxcr3 Human Pre-designed siRNA Set | siRNA |
| C-X-C motif chemokine receptor 3 | ||
| Human cxcr3 Pre-designed siRNA Set contains three designed siRNAs for cxcr3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 2833 | ||
| M60380 | CXCR2 Human Pre-designed siRNA Set | siRNA |
| C-X-C motif chemokine receptor 2 | ||
| Human CXCR2 Pre-designed siRNA Set contains three designed siRNAs for CXCR2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 3579 | ||
| M61396 | CXCR4 Human Pre-designed siRNA Set | siRNA |
| C-X-C motif chemokine receptor 4 | ||
| Human CXCR4 Pre-designed siRNA Set contains three designed siRNAs for CXCR4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 7852 | ||
| M62549 | ACKR3 Human Pre-designed siRNA Set | siRNA |
| atypical chemokine receptor 3 | ||
| Human ACKR3 Pre-designed siRNA Set contains three designed siRNAs for ACKR3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 57007 | ||
| M64472 | CXCR1 Human Pre-designed siRNA Set | siRNA |
| C-X-C motif chemokine receptor 1 | ||
| Human CXCR1 Pre-designed siRNA Set contains three designed siRNAs for CXCR1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 3577 | ||
| M65101 | Cxcr2 Mouse Pre-designed siRNA Set | siRNA |
| C-X-C motif chemokine receptor 2 | ||
| Mouse Cxcr2 Pre-designed siRNA Set contains three designed siRNAs for Cxcr2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 12765 | ||
| M65305 | CXCR5 Human Pre-designed siRNA Set | siRNA |
| C-X-C motif chemokine receptor 5 | ||
| Human CXCR5 Pre-designed siRNA Set contains three designed siRNAs for CXCR5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 643 | ||
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