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JDQ443

Cat. No. M11016

All AbMole products are for research use only, cannot be used for human consumption.

JDQ443  Structure
Synonym:

NVP-JDQ443; Opnurasib

Size Price Availability Quantity
1mg USD 160  USD160 In stock
5mg USD 470  USD470 In stock
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Quality Control & Documentation
Biological Activity

JDQ-443 (example 1a) is a covalent inhibitor of KRAS G12C.

Chemical Information
Molecular Weight 526.03
Formula C₂₉H₂₈ClN₇O
CAS Number 2653994-08-0
Form Solid
Solubility (25°C) DMSO ≥ 200 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Andreas Weiss, et al. Cancer Discov. Discovery, Preclinical Characterization, and Early Clinical Activity of JDQ443, a Structurally Novel, Potent, and Selective Covalent Oral Inhibitor of KRASG12C

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  Catalog
Abmole Inhibitor Catalog




Keywords: JDQ443 , NVP-JDQ443; Opnurasib supplier, Ras, inhibitors, activators

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