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IWP-O1 is a porcn inhibitor with an EC50 value of 80 pM in a cultured cell reporter assay of Wnt signaling and effectively suppresses the phosphorylation of Dvl2/3 in HeLa cells.
| Molecular Weight | 432.48 |
| Formula | C26H20N6O |
| CAS Number | 2074607-48-8 |
| Solubility (25°C) | DMSO 86 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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