All AbMole products are for research use only, cannot be used for human consumption.
IWP-L6 is a highly potent Porcn inhibitor with EC50 of 0.5 nM.
Nucleic Acids Res. 2024 Feb;gkae057.
Selection-free precise gene repair using high-capacity adenovector delivery of advanced prime editing systems rescues dystrophin synthesis in DMD muscle cells
IWP-L6 purchased from AbMole
bioRxiv. 2024 Jun 24.
Organs-on-chip: towards therapies for cardiovascular disease using human stem cells
IWP-L6 purchased from AbMole
Nucleic Acids Res. 2022 Jul 22;50(13):7761-7782.
Large-scale genome editing based on high-capacity adenovectors and CRISPR-Cas9 nucleases rescues full-length dystrophin synthesis in DMD muscle cells
IWP-L6 purchased from AbMole
Cell Reports Methods. 2022 Oct 24.
STRAIGHT-IN enables high-throughput targeting of large DNA payloads in human pluripotent stem cells
IWP-L6 purchased from AbMole
Stem Cell Res. 2020 Mar;43:101698.
Cryopreservation of human pluripotent stem cell-derived cardiomyocytes is not detrimental to their molecular and functional properties.
IWP-L6 purchased from AbMole
| Molecular Weight | 472.58 |
| Formula | C25H20N4O2S2 |
| CAS Number | 1427782-89-5 |
| Solubility (25°C) | DMSO ≥ 15 mg/mL (with 50ºC water bath) |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Wnt/beta-catenin Products |
|---|
| (9Z,12Z,15Z)-N-[(3-Methoxyphenyl)methyl]-9,12,15-octadecatrienamide
(9Z,12Z,15Z)-N-[(3-Methoxyphenyl)methyl]-9,12,15-octadecatrienamide is a macamide isolated from Maca (Lepidium meyenii Walp). (9Z,12Z,15Z)-N-[(3-Methoxyphenyl)methyl]-9,12,15-octadecatrienamide induces mesenchymal stem cells osteogenic differentiation and consequent bone formation through activating the canonical Wnt/β‐catenin signaling pathway. |
| F7H
F7H is a Frizzled receptor FZD7 antagonist with IC50 of 1.25 μM. F7H is a potent ligand for the FZD7 transmembrane domain (TMD). |
| UU-T02
UU-T02 is a novel potent, selective small-molecule inhibitor of β-Catenin/T-cell factor protein-protein interaction, with a Ki of 1.36 μM. UU-T02 inhibits canonical Wnt signaling. |
| Wnt/β-catenin agonist 1
Wnt/β-catenin agonist 1 is a Wnt/β-catenin signalling pathway agonist, with an EC50 of 0.27 μM. |
| Calphostin C
Calphostin C (PKF115-584) is a small molecule inhibitor of Wnt/beta-catenin/lef-1 signaling. Calphostin C is also a potent and specific inhibitor of protein kinase C. PKF115-584 efficiently killed CLL cells (LC(50)<1 microM), whereas normal B cells were not significantly affected. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
