Free shipping on all orders over $ 500

Imiquimod hydrochloride

Cat. No. M14128

All AbMole products are for research use only, cannot be used for human consumption.

Imiquimod hydrochloride Structure
Synonym:

R 837 hydrochloride

Size Price Availability Quantity
100mg USD 60  USD60 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Imiquimod hydrochloride (R 837 hydrochloride), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod hydrochloride exhibits antiviral and antitumor effects in vivo. Imiquimod hydrochloride can be used for the research of external genital, perianal warts, cancer and COVID-19.

Chemical Information
Molecular Weight 276.76
CAS Number 99011-78-6
Solubility (25°C) DMSO 8 mg/mL (ultrasonic and warming and heat to 50°C)
Water 4.8 mg/mL
Storage 2-8°C, dry, sealed
References

[1] Iori Okura, et al. Fingolimod ameliorates imiquimod-induced psoriasiform dermatitis by sequestrating interleukin-17-producing ?d T cells in secondary lymph nodes

[2] Kent Sakai, et al. Mouse model of imiquimod-induced psoriatic itch

[3] M Bayes, et al. Gateways to Clinical Trials. June 2002

[4] M Bayes, et al. Gateways to clinical trials

[5] M Bayes, et al. Gateways to Clinical Trials

Related TLR Products
Pepinh-TRIF TFA

Pepinh-TRIF TFA blocks TIR-domain-containing adapter-inducing interferon-β (TRIF) signaling by interfering with TLR-TRIF interaction.

CAY10614

CAY10614 is a potent TLR4 antagonist. CAY10614 inhibits the lipid A-induced activation of TLR4, with an IC50 of 1.675 μM.

TLR4-IN-C34-C2-COOH

TLR4-IN-C34-C2-COO is a linker that incorporates TLR4 inhibitor TLR4-IN-C34. TLR4-IN-C34 inhibits TLR4 in enterocytes and macrophages, and reduces systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis.

BNT411 

BNT411 is a selective TLR7 agonist that can induce the release of IFNa both in vivo and in vitro.

Rabeximod

Rabeximod (ROB-803), an anti-rheumatic compound, impairs the differentiation and function of human pro-inflammatory dendritic cells and macrophages via downregulating TLR2 and TLR4 stimulation.

  Catalog
Abmole Inhibitor Catalog




Keywords: Imiquimod hydrochloride, R 837 hydrochloride supplier, TLR, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.