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iFSP1

Cat. No. M11314

All AbMole products are for research use only, cannot be used for human consumption.

iFSP1  Structure
Size Price Availability Quantity
5mg USD 33  USD33 In stock
10mg USD 53  USD53 In stock
50mg USD 230  USD230 In stock
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Quality Control & Documentation
Biological Activity

IFSP1 is an effective, selective and glutathione-independent inhibitor of ferroptosis Suppressor protein 1 (FSP1/AIFM2) with an EC50 value of 103 nM. IFSP1 can selectively induce iron death in Pfa1 cells and HT1080 cells with GPX4 knockout gene overexpressing FSP1.

Chemical Information
Molecular Weight 323.35
Formula C20H13N5
CAS Number 150651-39-1
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Ara Jo, et al. Cell Death Dis. Plasma-activated medium induces ferroptosis by depleting FSP1 in human lung cancer cells

Related Ferroptosis Products
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viFSP1 is a species-independent inhibitor of FSP1 that induces ferroptosis in FSP1-dependent cells.

icFSP1 

icFSP1 is a potent ferroptosis suppressor protein-1 (FSP1) inhibitor.

(R)-HTS-3 

(R)-HTS-3 is an lysophosphatidylcholine acyltransferase 3 (LPCAT3) inhibitor, with an IC50 of 0.09 μM.

CuATSP

CuATSP is a potent inhibitor of ferroptosis.

  Catalog
Abmole Inhibitor Catalog




Keywords: iFSP1 supplier, Ferroptosis, inhibitors, activators

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