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IFSP1 is an effective, selective and glutathione-independent inhibitor of ferroptosis Suppressor protein 1 (FSP1/AIFM2) with an EC50 value of 103 nM. IFSP1 can selectively induce iron death in Pfa1 cells and HT1080 cells with GPX4 knockout gene overexpressing FSP1.
| Molecular Weight | 323.35 |
| Formula | C20H13N5 |
| CAS Number | 150651-39-1 |
| Solubility (25°C) | DMSO ≥ 60 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Ferroptosis Products |
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CuATSP is a potent inhibitor of ferroptosis. |
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YL-939 is a novel non-classical and specific ferroptosis inhibitor, targets and binds directly to the prohibitin 2 (PHB2) protein with Kd of 3.43 uM in SPR assays. |
| Butylated hydroxytoluene
Butylated hydroxytoluene is an antioxidant. Butylated hydroxytoluene is a ferroptosis inhibitor. |
| PRDX3(103-112) SO3 modified, human
PRDX3(103-112) SO3 modified, human is a marker of ferroptosis, and can be used for liver diseases study. |
| PRDX3(103-112), human
PRDX3(103-112), human is a marker for ferroptosis. |
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