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GSK1795091

Cat. No. M28000

All AbMole products are for research use only, cannot be used for human consumption.

GSK1795091 Structure
Synonym:

CRX-601

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Quality Control & Documentation
Biological Activity

GSK1795091 (CRX-601), an immunologic stimulator, is a synthetic TLR4 agonist. Antitumor activity. GSK1795091 can be used as a vaccine adjuvant to enhance both mucosal and systemic immunity to influenza virus vaccines.

Chemical Information
Molecular Weight 1446.09
Formula C81H157N2O16P
CAS Number 1233589-81-5
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Neeltje Steeghs, et al. Clin Transl Sci. Manufacturing-dependent change in biological activity of the TLR4 agonist GSK1795091 and implications for lipid A analog development

[2] Bruce A Hug, et al. Clin Ther. Safety, Pharmacokinetics, and Pharmacodynamics of the TLR4 Agonist GSK1795091 in Healthy Individuals: Results from a Randomized, Double-blind, Placebo-controlled, Ascending Dose Study

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Keywords: GSK1795091, CRX-601 supplier, TLR, inhibitors, activators

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