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Gomisin-J

Cat. No. M4256

All AbMole products are for research use only, cannot be used for human consumption.

Gomisin-J Structure
Size Price Availability Quantity
5mg USD 150  USD150 In stock
10mg USD 250  USD250 In stock
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Quality Control & Documentation
Biological Activity

Gomisin J isa small molecular weight lignan found in Schisandra chinensis with vasodilatory activity. Gomisin J regulates lipogenesis, lipolytic enzyme and inflammatory molecule expression to inhibit lipid accumulation by activating AMPK, LKB1 and Ca2+/ Calmodulin-dependent protein kinase II and inhibiting Fetuin-A in HepG2 cells. Gomisin J has potential benefits in the study of non-alcoholic fatty liver disease.

Chemical Information
Molecular Weight 388.45
Formula C22H28O6
CAS Number 66280-25-9
Storage 4°C, protect from light, dry, sealed
References

[1] Ruilong Li, et al. Gomisin J inhibits the glioma progression by inducing apoptosis and reducing HKII-regulated glycolysis

[2] Samil Jung, et al. Anticancer activity of gomisin J from Schisandra chinensis fruit

[3] Myungsuk Kim, et al. Gomisin J Inhibits Oleic Acid-Induced Hepatic Lipogenesis by Activation of the AMPK-Dependent Pathway and Inhibition of the Hepatokine Fetuin-A in HepG2 Cells

[4] Ji Young Park, et al. Gomisin J from Schisandra chinensis induces vascular relaxation via activation of endothelial nitric oxide synthase

[5] Su-Yeon Oh, et al. Anti-inflammatory effects of gomisin N, gomisin J, and schisandrin C isolated from the fruit of Schisandra chinensis

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Keywords: Gomisin-J supplier, AMPK, inhibitors, activators

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