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Gomisin J isa small molecular weight lignan found in Schisandra chinensis with vasodilatory activity. Gomisin J regulates lipogenesis, lipolytic enzyme and inflammatory molecule expression to inhibit lipid accumulation by activating AMPK, LKB1 and Ca2+/ Calmodulin-dependent protein kinase II and inhibiting Fetuin-A in HepG2 cells. Gomisin J has potential benefits in the study of non-alcoholic fatty liver disease.
Molecular Weight | 388.45 |
Formula | C22H28O6 |
CAS Number | 66280-25-9 |
Storage | 4°C, protect from light, dry, sealed |
[2] Samil Jung, et al. Anticancer activity of gomisin J from Schisandra chinensis fruit
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