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Foxy-5, a WNT5A agonist and a mimetic peptide of WNT5A, triggers cytoplasmic free calcium signaling without affecting β-catenin activation and inhibits migration and invasion of epithelial cancer cells.Foxy-5 effectively reduces metastatic spread of prostate cancer cells with low WNT5A expression in an in situ mouse model.
| Molecular Weight | 694.77 |
| Formula | C26H42N6O12S2 |
| CAS Number | 881188-51-8 |
| Form | Solid |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Rebecca Kelsey. Nat Rev Urol. Prostate cancer: Foxy-5 in prostate cancer model
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