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Etilevodopa (L-Dopa ethyl ester) hydrochloride, an ethyl-ester proagent of Levodopa, is rapidly hydrolyzed to Levodopa and ethanol by nonspecific esterases in the gastrointestinal tract. Etilevodopa hydrochloride is used for the treatment of Parkinson disease (PD). Levodopa is the direct precursor of dopamine and is a suitable proagent as it facilitates CNS penetration and delivers dopamine.
Molecular Weight | 261.7 |
Formula | C11H16ClNO4 |
CAS Number | 39740-30-2 |
Form | Solid |
Solubility (25°C) | Water 125 mg/mL (ultrasonic) |
Storage | 4°C, protect from light, sealed |
[1] M Bayés, et al. Methods Find Exp Clin Pharmacol. Gateways to clinical trials
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