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Etalocib (LY293111), an orally active leukotriene B4 receptor antagonist, inhibits the binding of [3H]LTB4, with a Ki of 25 nM. Etalocib (LY293111) prevents LTB4-induced calcium mobilization with an lC50 of 20 nM. Etalocib (LY293111) induces apoptosis.
| Molecular Weight | 544.61 |
| Formula | C33H33FO6 |
| CAS Number | 161172-51-6 |
| Form | Solid |
| Solubility (25°C) | DMSO 100 mg/mL (ultrasonic) |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[3] M Bayes, et al. Methods Find Exp Clin Pharmacol. Gateways to clinical trials
[4] Xian-Zhong Ding, et al. Anticancer Drugs. A novel anti-pancreatic cancer agent, LY293111
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