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LY255283 is a competitive leukotriene B4 receptor antagonist, with an IC50 of about 100 nM. It is somewhat selective for the BLT2 receptor, since IC50 values at the BLT1 receptor are >10 μM. LY255283 reduces airway obstruction in animal models of asthma.
| Molecular Weight | 360.45 |
| Formula | C19H28N4O3 |
| CAS Number | 117690-79-6 |
| Solubility (25°C) | DMSO: ≥20 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[4] S A Silbaugh, et al. Pulmonary actions of LY255283, a leukotriene B4 receptor antagonist
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