All AbMole products are for research use only, cannot be used for human consumption.
CP-424174 is a cytokine release inhibitory compounds (CRID) that inhibits the post-translational processing and secretion of IL-1b in response to LPS and ATP in human monocytes. It is quite possible that similarly to CP-456,773 (termed CRID3), CP-424,174 inhibits both NLRP3 and AIM2 inflammasomes by preventing ASC oligomerisation.
| Molecular Weight | 452.99 |
| Formula | C22H29ClN2O4S |
| CAS Number | 210825-31-3 |
| Solubility (25°C) | DMSO: 20 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Leukotriene Receptor Products |
|---|
| Ablukast
Ablukast (Ro 23-3544) is a specific and active leukotriene receptor antagonist. |
| BIIL-260
BIIL-260 is a potent and long-acting orally active leukotriene B(4) receptor LTB4 antagonist, with anti-inflammatory activity. |
| Olsalazine
Olsalazine is a potent inhibitor of macrophages chemotaxis to LTB4 with an IC50 value of 0.39 mM. |
| HAMI 3379
HAMI 3379 is a potent and selective CysLT2 receptor antagonist. |
| FPL-55712 free base
FPL-55712 free base is a leukotriene receptor antagonist. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
