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Claficapavir (A1752) is a specific nucleocapsid protein (NC) inhibitor with an IC50 around 1 μM. Claficapavir strongly binds the HIV-1 NC (Kd=20 nM) thereby inhibiting the chaperone properties of NC and leading to good antiviral activity against the HIV-1.
| Molecular Weight | 393.86 |
| Formula | C17H12ClNO4S2 |
| CAS Number | 2055732-24-4 |
| Form | Solid |
| Solubility (25°C) | DMSO 200 mg/mL (ultrasonic and warming and heat to 40°C) |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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