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Cambinol is an inhibitor of SIRT1 and SIRT2 with IC50 values of 56 μM and 59 μM, respectively. Cambinol also inhibited exosome release.
| Molecular Weight | 360.43 |
| Formula | C21H16N2O2S |
| CAS Number | 14513-15-6 |
| Form | Solid |
| Solubility (25°C) | DMSO: ≥10 mg/mL |
| Storage | -20°C, protect from light |
[3] Xinfa Bai, et al. Small Molecules as SIRT Modulators
[5] Jos M Villalba, et al. Sirtuin activators and inhibitors
| Related Sirtuin Products |
|---|
| SIRT1-IN-1
SIRT1-IN-1 is a selective SIRT1 inhibitor with an IC50 of 0.205 μM. |
| Sirtuin-1 inhibitor 1
Sirtuin-1 inhibitor 1 is an inhibitor of Sirtuin-1 that plays important roles in obesity-induced diabetes and aging-related diseases. |
| ADTL-SA1215
ADTL-SA1215 is a first-in-class, specific small molecule activator of SIRT3 that modulates autophagy in triple-negative breast cancer. |
| SIRT2/6-IN-1
SIRT2/6-IN-1 is a SIRT6/SIRT2 inhibitor, with IC50s of 106 μM and 114 μM. |
| SIRT6-IN-2
SIRT6-IN-2 is a selective SIRT6 inhibitor (IC50: 34 μM). |
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