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Buformin hydrochloride

Cat. No. M13808

All AbMole products are for research use only, cannot be used for human consumption.

Buformin hydrochloride Structure
Synonym:

1-Butylbiguanide hydrochloride

Price and Availability

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Quality Control & Documentation
Biological Activity

Buformin hydrochloride (1-Butylbiguanide hydrochloride), a potent AMPK activator, acts as an orally active biguanide antidiabetic agent. Buformin hydrochloride decreases hepatic gluconeogenesis and lowers blood glucose production in vivo. Buformin hydrochloride also has anti-cancer activities and is applied in cancer study (such as, cervical cancer and breast cancer, et al).

Chemical Information
Molecular Weight 193.68
CAS Number 1190-53-0
Solubility (25°C) DMSO 90 mg/mL
Water 90 mg/mL
Storage 2-8°C, sealed
References

[1] Michał Krzysztof Kołodziejczyk, et al. Polim Med. [The use of natural and synthetic hydrophilic polymers in the formulation of metformin hydrochloride tablets with different profile release]

[2] Y Sawayanagi, et al. Chem Pharm Bull (Tokyo). Sustained-release formulation of buformin hydrochloride

[3] J A Wickramasinghe, et al. J Chromatogr. Gas chromatographic behavior of buformin hydrochloride, phenformin hydrochloride and phenylbiguanide. The pyrolytic formation of substituted 2,4,6-triamino-1,3,5-triazines from biguanides

[4] P Singer, et al. Z Gesamte Inn Med. [Comparative studies of the effect of N1-n-butylbiguanide hydrochloride (Buformin) and N1-n-butylbiguanide tosylate (Buformin retard)]

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Keywords: Buformin hydrochloride, 1-Butylbiguanide hydrochloride supplier, AMPK, inhibitors, activators

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